DIRAS3 Full-Length MS Protein Standard


Product Description:

Name DIRAS3 Full-Length MS Protein Standard
Cat# CPFL302787
Protein NameDIRAS family, GTP-binding RAS-like 3
SymbolDIRAS3
SynonymsARHI; NOEY2
AccessionNM_004675
Cytogenetic1p31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW25.7 kDa
Expression TrueORF CloneRC202787
DescriptionDIRAS3 Full-Length MS Protein Standard (NP_004666), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

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