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NFYB Full-Length MS Protein Standard

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Product Description


NameNFYB Full-Length MS Protein Standard
Cat#CPFL302749
Protein Namenuclear transcription factor Y, beta
SymbolNFYB
SynonymsCBF-A; CBF-B; HAP3; NF-YB
AccessionNM_006166
Cytogenetic12q22-q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNFYB Full-Length MS Protein Standard (NP_006157), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.

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