Home > Products > Stable Isotope Labeled Full Length MS Protein Standard > HUS1 Full-Length MS Protein Standard

HUS1 Full-Length MS Protein Standard

INQUIRY>

Product Description


NameHUS1 Full-Length MS Protein Standard
Cat#CPFL302727
Protein NameHUS1 checkpoint homolog
SymbolHUS1
SynonymshHUS1
AccessionNM_004507
Cytogenetic7p13-p12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHUS1 Full-Length MS Protein Standard (NP_004498), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.

Products List:

Cat#Protein SequencePrice

If the product of interest is not available in our catalog, we can synthesize for you with our quality controlled
Customized Synthesized Peptide/Proteins Service!

Online Inquiry


Please input "proteomics" as verification code.