UQCRB Full-Length MS Protein Standard

Product Information
Protein Name
ubiquinol-cytochrome c reductase binding protein
Description
UQCRB Full-Length MS Protein Standard (NP_006285), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X.
Symbol
UQCRB
Synonyms
MC3DN3; QCR7; QP-C; QPC; UQBC; UQBP; UQCR6; UQPC
Accession
NM_006294
Cytogenetic
8q22
Amino Acid Labeled
[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression Host
Human HEK293 cells
Predicted MW
13.3 kDa
Expression True or False Clone
RC202685
Protein Sequence
>RC202685 representing NM_006294
MAGKQAVSASGKWLDGIRKWYYNAAGFNKLGLMRDDTIYEDEDVKEAIRRLPENLYNDRMFRIKRALDLN
LKHQILPKEQWTKYEEENFYLEPYLKEVIRERKEREEWAKK

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