ANAPC10 Full-Length MS Protein Standard


Product Description:

Name ANAPC10 Full-Length MS Protein Standard
Cat# CPFL302679
Protein Nameanaphase promoting complex subunit 10
SymbolANAPC10
SynonymsAPC10; DOC1
AccessionNM_014885
Cytogenetic4q31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW21.1 kDa
Expression TrueORF CloneRC202679
DescriptionANAPC10 Full-Length MS Protein Standard (NP_055700), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 )

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