FERMT3 Full-Length MS Protein Standard


Product Description:

Name FERMT3 Full-Length MS Protein Standard
Cat# CPFL302580
Protein NameFERMT3 fermitin family member 3 [ Homo sapiens ]
SymbolFERMT3
SynonymsKIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF
AccessionNM_031471
Cytogenetic11q13.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW75.2 kDa
Expression TrueORF CloneRC202580
DescriptionFERMT3 Full-Length MS Protein Standard (NP_113659), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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