HEY2 Full-Length MS Protein Standard


Product Description:

Name HEY2 Full-Length MS Protein Standard
Cat# CPFL302544
Protein Namehes-related family bHLH transcription factor with YRPW motif 2
SymbolHEY2
SynonymsbHLHb32; CHF1; GRIDLOCK; GRL; HERP1; HESR2; HRT2
AccessionNM_012259
Cytogenetic6q21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW35.6 kDa
Expression TrueORF CloneRC202544
DescriptionHEY2 Full-Length MS Protein Standard (NP_036391), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

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