HOOK1 Full-Length MS Protein Standard


Product Description:

Name HOOK1 Full-Length MS Protein Standard
Cat# CPFL302517
Protein Namehook homolog 1
SymbolHOOK1
SynonymsHK1
AccessionNM_015888
Cytogenetic1p32.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW84.5 kDa
Expression TrueORF CloneRC202517
DescriptionHOOK1 Full-Length MS Protein Standard (NP_056972), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.

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