ACTR1B Full-Length MS Protein Standard


Product Description:

Name ACTR1B Full-Length MS Protein Standard
Cat# CPFL302493
Protein NameARP1 actin-related protein 1 homolog B, centractin beta (yeast)
SymbolACTR1B
SynonymsARP1B; CTRN2; PC3
AccessionNM_005735
Cytogenetic2q11.1-q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW42.1 kDa
Expression TrueORF CloneRC202493
DescriptionACTR1B Full-Length MS Protein Standard (NP_005726), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.

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