IL17RA Full-Length MS Protein Standard


Product Description:

Name IL17RA Full-Length MS Protein Standard
Cat# CPFL302390
Protein Nameinterleukin 17 receptor A
SymbolIL17RA
SynonymsCANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R
AccessionNM_014339
Cytogenetic22q11.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW93.2 kDa
Expression TrueORF CloneRC202390
DescriptionIL17RA Full-Length MS Protein Standard (NP_055154), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

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