HMGN3 Full-Length MS Protein Standard


Product Description:

Name HMGN3 Full-Length MS Protein Standard
Cat# CPFL302339
Protein Namehigh mobility group nucleosomal binding domain 3
SymbolHMGN3
SynonymsPNAS-24; PNAS-25; TRIP7
AccessionNM_138730
Cytogenetic6q14.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW8.2 kDa
Expression TrueORF CloneRC202339
DescriptionHMGN3 Full-Length MS Protein Standard (NP_620058), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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