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ATL1 Full-Length MS Protein Standard

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Product Description


NameATL1 Full-Length MS Protein Standard
Cat#CPFL302310
Protein Nameatlastin GTPase 1
SymbolATL1
SynonymsAD-FSP; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A
AccessionNM_015915
Cytogenetic14q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionATL1 Full-Length MS Protein Standard (NP_056999), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

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