MFN2 Full-Length MS Protein Standard


Product Description:

Name MFN2 Full-Length MS Protein Standard
Cat# CPFL302218
Protein Namemitofusin 2
SymbolMFN2
SynonymsCMT2A; CMT2A2; CPRP1; HSG; MARF
AccessionNM_014874
Cytogenetic1p36.22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW86.2 kDa
Expression TrueORF CloneRC202218
DescriptionMFN2 Full-Length MS Protein Standard (NP_055689), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

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