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GALT Full-Length MS Protein Standard

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Product Description


NameGALT Full-Length MS Protein Standard
Cat#CPFL302206
Protein Namegalactose-1-phosphate uridylyltransferase
SymbolGALT
SynonymsOTTHUMP00000021298; galactose-1-phosphate uridyl transferase; galactose-1-phosphate uridylyltransferase
AccessionNM_000155
Cytogenetic9p13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGALT Full-Length MS Protein Standard (NP_000146), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.

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