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FKBP3 Full-Length MS Protein Standard

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Product Description


NameFKBP3 Full-Length MS Protein Standard
Cat#CPFL302200
Protein NameFK506 binding protein 3, 25kDa
SymbolFKBP3
SynonymsFKBP-25; FKBP-3; FKBP25; PPIase
AccessionNM_002013
Cytogenetic14q21.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionFKBP3 Full-Length MS Protein Standard (NP_002004), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

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