BCHE Full-Length MS Protein Standard


Product Description:

Name BCHE Full-Length MS Protein Standard
Cat# CPFL302198
Protein Namebutyrylcholinesterase
SymbolBCHE
SynonymsCHE1; CHE2; E1
AccessionNM_000055
Cytogenetic3q26.1-q26.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW68.2 kDa
Expression TrueORF CloneRC202198
DescriptionBCHE Full-Length MS Protein Standard (NP_000046), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

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