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IFI16 Full-Length MS Protein Standard

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Product Description


NameIFI16 Full-Length MS Protein Standard
Cat#CPFL302193
Protein Nameinterferon, gamma-inducible protein 16
SymbolIFI16
SynonymsIFNGIP1; PYHIN2
AccessionNM_005531
Cytogenetic1q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIFI16 Full-Length MS Protein Standard (NP_005522), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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