KEAP1 Full-Length MS Protein Standard


Product Description:

Name KEAP1 Full-Length MS Protein Standard
Cat# CPFL302189
Protein Namekelch-like ECH-associated protein 1
SymbolKEAP1
SynonymsINrf2; KLHL19
AccessionNM_203500
Cytogenetic19p13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW69.5 kDa
Expression TrueORF CloneRC202189
DescriptionKEAP1 Full-Length MS Protein Standard (NP_987096), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

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