UGDH Full-Length MS Protein Standard


Product Description:

Name UGDH Full-Length MS Protein Standard
Cat# CPFL302132
Protein NameUDP-glucose 6-dehydrogenase
SymbolUGDH
SynonymsGDH; UDP-GlcDH; UDPGDH; UGD
AccessionNM_003359
Cytogenetic4p15.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW54.8 kDa
Expression TrueORF CloneRC202132
DescriptionUGDH Full-Length MS Protein Standard (NP_003350), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.

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