FA2H Full-Length MS Protein Standard


Product Description:

Name FA2H Full-Length MS Protein Standard
Cat# CPFL302093
Protein Namefatty acid 2-hydroxylase
SymbolFA2H
SynonymsFAAH; FAH1; FAXDC1; SCS7; SPG35
AccessionNM_024306
Cytogenetic16q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW42.6 kDa
Expression TrueORF CloneRC202093
DescriptionFA2H Full-Length MS Protein Standard (NP_077282), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.

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