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CASP7 Full-Length MS Protein Standard

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Product Description


NameCASP7 Full-Length MS Protein Standard
Cat#CPFL302059
Protein Namecaspase 7, apoptosis-related cysteine peptidase
SymbolCASP7
SynonymsCASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
AccessionNM_033339
Cytogenetic10q25
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCASP7 Full-Length MS Protein Standard (NP_203125), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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