DNM1L Full-Length MS Protein Standard


Product Description:

Name DNM1L Full-Length MS Protein Standard
Cat# CPFL302046
Protein Namedynamin 1-like
SymbolDNM1L
SynonymsDLP1; DRP1; DVLP; DYMPLE; EMPF; HDYNIV
AccessionNM_012063
Cytogenetic12p11.21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW79.3 kDa
Expression TrueORF CloneRC202046
DescriptionDNM1L Full-Length MS Protein Standard (NP_036193), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimers disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

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