BMX Full-Length MS Protein Standard


Product Description:

Name BMX Full-Length MS Protein Standard
Cat# CPFL302002
Protein NameBMX non-receptor tyrosine kinase
SymbolBMX
SynonymsETK; PSCTK2; PSCTK3
AccessionNM_203281
CytogeneticXp22.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW77.8 kDa
Expression TrueORF CloneRC202002
DescriptionBMX Full-Length MS Protein Standard (NP_975010), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.

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