CLN6 Full-Length MS Protein Standard


Product Description:

Name CLN6 Full-Length MS Protein Standard
Cat# CPFL301904
Protein Nameceroid-lipofuscinosis, neuronal 6, late infantile, variant
SymbolCLN6
SynonymsCLN4A; HsT18960; nclf
AccessionNM_017882
Cytogenetic15q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW35.7 kDa
Expression TrueORF CloneRC201904
DescriptionCLN6 Full-Length MS Protein Standard (NP_060352), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

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