Home > Products > Stable Isotope Labeled Full Length MS Protein Standard > TDP1 Full-Length MS Protein Standard

TDP1 Full-Length MS Protein Standard

INQUIRY>

Product Description


NameTDP1 Full-Length MS Protein Standard
Cat#CPFL301888
Protein Nametyrosyl-DNA phosphodiesterase 1
SymbolTDP1
SynonymsFLJ11090; MGC104252
AccessionNM_001008744
Cytogenetic14q32.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionTDP1 Full-Length MS Protein Standard (NP_001008744), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

Products List:

Cat#Protein SequencePrice

If the product of interest is not available in our catalog, we can synthesize for you with our quality controlled
Customized Synthesized Peptide/Proteins Service!

Online Inquiry


Please input "proteomics" as verification code.