SAE1 Full-Length MS Protein Standard
Product Description:
| Name |
SAE1 Full-Length MS Protein Standard |
| Cat# |
CPFL301820 |
| Protein Name | SUMO1 activating enzyme subunit 1 |
| Symbol | SAE1 |
| Synonyms | AOS1; HSPC140; SUA1; UBLE1A |
| Accession | NM_005500 |
| Cytogenetic | 19q13.32 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 38.3 kDa |
| Expression TrueORF Clone | RC201820 |
| Description | SAE1 Full-Length MS Protein Standard (NP_005491), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 ) |
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