FUS Full-Length MS Protein Standard


Product Description:

Name FUS Full-Length MS Protein Standard
Cat# CPFL301808
Protein Namefused in sarcoma
SymbolFUS
SynonymsALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS
AccessionNM_004960
Cytogenetic16p11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW53.2 kDa
Expression TrueORF CloneRC201808
DescriptionFUS Full-Length MS Protein Standard (NP_004951), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

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