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COX7C Full-Length MS Protein Standard

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Product Description


NameCOX7C Full-Length MS Protein Standard
Cat#CPFL301768
Protein NameCOX7C cytochrome c oxidase subunit VIIc [ Homo sapiens ]
SymbolCOX7C
Synonymscytochrome-c oxidase chain VIIc; cytochrome c oxidase subunit VIIc
AccessionNM_001867
Cytogenetic5q14
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCOX7C Full-Length MS Protein Standard (NP_001858), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13.

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