Name | CMBL Full-Length MS Protein Standard |
Cat# | CPFL301711 |
Protein Name | carboxymethylenebutenolidase homolog (Pseudomonas) |
Symbol | CMBL |
Synonyms | JS-1 |
Accession | NM_138809 |
Cytogenetic | 5p15.2 |
Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Expression Host | Human HEK293 cells |
Predicted MW | 27.9 kDa |
Expression TrueORF Clone | RC201711 |
Description | CMBL Full-Length MS Protein Standard (NP_620164), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 ) |
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