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PDK4 Full-Length MS Protein Standard

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Product Description


NamePDK4 Full-Length MS Protein Standard
Cat#CPFL301656
Protein Namepyruvate dehydrogenase kinase, isozyme 4
SymbolPDK4
SynonymsFLJ40832
AccessionNM_002612
Cytogenetic7q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPDK4 Full-Length MS Protein Standard (NP_002603), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

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