LIPA Full-Length MS Protein Standard


Product Description:

Name LIPA Full-Length MS Protein Standard
Cat# CPFL301637
Protein Namelipase A, lysosomal acid, cholesterol esterase
SymbolLIPA
SynonymsCESD; LAL
AccessionNM_000235
Cytogenetic10q23.2-q23.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW43 kDa
Expression TrueORF CloneRC201637
DescriptionLIPA Full-Length MS Protein Standard (NP_000226), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene.

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