NCOA4 Full-Length MS Protein Standard


Product Description:

Name NCOA4 Full-Length MS Protein Standard
Cat# CPFL301606
Protein Namenuclear receptor coactivator 4
SymbolNCOA4
SynonymsARA70; ELE1; PTC3; RFG
AccessionNM_005437
Cytogenetic10q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW69.5 kDa
Expression TrueORF CloneRC201606
DescriptionNCOA4 Full-Length MS Protein Standard (NP_005428), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

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