ORC4 Full-Length MS Protein Standard


Product Description:

Name ORC4 Full-Length MS Protein Standard
Cat# CPFL301587
Protein Nameorigin recognition complex, subunit 4
SymbolORC4
SynonymsORC4L; ORC4P
AccessionNM_002552
Cytogenetic2q22-q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW50.2 kDa
Expression TrueORF CloneRC201587
DescriptionORC4L Full-Length MS Protein Standard (NP_002543), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

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