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IRF6 Full-Length MS Protein Standard

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Product Description


NameIRF6 Full-Length MS Protein Standard
Cat#CPFL301579
Protein Nameinterferon regulatory factor 6
SymbolIRF6
SynonymsLPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
AccessionNM_006147
Cytogenetic1q32.3-q41
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIRF6 Full-Length MS Protein Standard (NP_006138), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

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