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NCBP2 Full-Length MS Protein Standard

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Product Description


NameNCBP2 Full-Length MS Protein Standard
Cat#CPFL301519
Protein Namenuclear cap binding protein subunit 2, 20kDa
SymbolNCBP2
SynonymsCBC2; CBP20; NIP1; PIG55
AccessionNM_007362
Cytogenetic3q29
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNCBP2 Full-Length MS Protein Standard (NP_031388), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5 cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.

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