AP2M1 Full-Length MS Protein Standard


Product Description:

Name AP2M1 Full-Length MS Protein Standard
Cat# CPFL301377
Protein Nameadaptor-related protein complex 2, mu 1 subunit
SymbolAP2M1
SynonymsAP50; CLAPM1; mu2
AccessionNM_001025205
Cytogenetic3q28
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW49.2 kDa
Expression TrueORF CloneRC201377
DescriptionAP2M1 Full-Length MS Protein Standard (NP_001020376), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene.

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