MYL12B Full-Length MS Protein Standard


Product Description:

Name MYL12B Full-Length MS Protein Standard
Cat# CPFL301372
Protein Namemyosin, light chain 12B, regulatory
SymbolMYL12B
SynonymsMLC-B; MRLC2
AccessionNM_033546
Cytogenetic18p11.31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW19.6 kDa
Expression TrueORF CloneRC201372
DescriptionMYL12B Full-Length MS Protein Standard (NP_291024), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 )

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