PAFAH1B3 Full-Length MS Protein Standard


Product Description:

Name PAFAH1B3 Full-Length MS Protein Standard
Cat# CPFL301268
Protein Nameplatelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
SymbolPAFAH1B3
SynonymsPAFAHG
AccessionNM_002573
Cytogenetic19q13.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW25.6 kDa
Expression TrueORF CloneRC201268
DescriptionPAFAH1B3 Full-Length MS Protein Standard (NP_002564), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.

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