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ATP6V1E1 Full-Length MS Protein Standard

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Product Description


NameATP6V1E1 Full-Length MS Protein Standard
Cat#CPFL301267
Protein NameATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
SymbolATP6V1E1
SynonymsATP6E; ATP6E2; ATP6V1E; P31; Vma4
AccessionNM_001696
Cytogenetic22q11.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionATP6V1E1 Full-Length MS Protein Standard (NP_001687), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.

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