|Name||TNNT2 Full-Length MS Protein Standard|
|Protein Name||troponin T type 2 (cardiac)|
|Synonyms||CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC|
|Amino Acid Labeled||[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys|
|Description||TNNT2 Full-Length MS Protein Standard (NP_001001431), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.|
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