BCS1L Full-Length MS Protein Standard


Product Description:

Name BCS1L Full-Length MS Protein Standard
Cat# CPFL301195
Protein NameBCS1-like (S. cerevisiae)
SymbolBCS1L
SynonymsBCS; BCS1; BJS; FLNMS; GRACILE; h-BCS; Hs.6719; MC3DN1; PTD
AccessionNM_004328
Cytogenetic2q33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW47.4 kDa
Expression TrueORF CloneRC201195
DescriptionBCS1L Full-Length MS Protein Standard (NP_004319), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Five alternatively spliced transcripts encoding the same protein have been described.

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