PEX16 Full-Length MS Protein Standard


Product Description:

Name PEX16 Full-Length MS Protein Standard
Cat# CPFL301115
Protein Nameperoxisomal biogenesis factor 16
SymbolPEX16
SynonymsPBD8A; PBD8B
AccessionNM_004813
Cytogenetic11p11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW38.5 kDa
Expression TrueORF CloneRC201115
DescriptionPEX16 Full-Length MS Protein Standard (NP_004804), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.

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