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PEX16 Full-Length MS Protein Standard

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Product Description


NamePEX16 Full-Length MS Protein Standard
Cat#CPFL301115
Protein Nameperoxisomal biogenesis factor 16
SymbolPEX16
SynonymsPBD8A; PBD8B
AccessionNM_004813
Cytogenetic11p11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPEX16 Full-Length MS Protein Standard (NP_004804), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.

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