GLI1 Full-Length MS Protein Standard


Product Description:

Name GLI1 Full-Length MS Protein Standard
Cat# CPFL301110
Protein NameGLI family zinc finger 1
SymbolGLI1
SynonymsGLI
AccessionNM_005269
Cytogenetic12q13.2-q13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW117.7 kDa
Expression TrueORF CloneRC201110
DescriptionGLI1 Full-Length MS Protein Standard (NP_005260), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

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