ARPC1B Full-Length MS Protein Standard


Product Description:

Name ARPC1B Full-Length MS Protein Standard
Cat# CPFL301103
Protein Nameactin related protein 2/3 complex, subunit 1B, 41kDa
SymbolARPC1B
SynonymsARC41; p40-ARC; p41-ARC
AccessionNM_005720
Cytogenetic7q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW40.8 kDa
Expression TrueORF CloneRC201103
DescriptionARPC1B Full-Length MS Protein Standard (NP_005711), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

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