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IVD Full-Length MS Protein Standard

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Product Description


NameIVD Full-Length MS Protein Standard
Cat#CPFL301077
Protein Nameisovaleryl-CoA dehydrogenase
SymbolIVD
SynonymsACAD2
AccessionNM_002225
Cytogenetic15q14-q15
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIVD Full-Length MS Protein Standard (NP_002216), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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