CENPM Full-Length MS Protein Standard


Product Description:

Name CENPM Full-Length MS Protein Standard
Cat# CPFL301047
Protein Namecentromere protein M
SymbolCENPM
SynonymsC22orf18; CENP-M; PANE1
AccessionNM_024053
Cytogenetic22q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW19.6 kDa
Expression TrueORF CloneRC201047
DescriptionCENPM Full-Length MS Protein Standard (NP_076958), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 )

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