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MICU1 Full-Length MS Protein Standard

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Product Description


NameMICU1 Full-Length MS Protein Standard
Cat#CPFL300921
Protein Namemitochondrial calcium uptake 1
SymbolMICU1
SynonymsCALC; CBARA1; EFHA3; MPXPS
AccessionNM_006077
Cytogenetic10q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCBARA1 Full-Length MS Protein Standard (NP_006068), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

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