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NEIL2 Full-Length MS Protein Standard

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Product Description


NameNEIL2 Full-Length MS Protein Standard
Cat#CPFL300913
Protein Namenei endonuclease VIII-like 2
SymbolNEIL2
SynonymsNEH2; NEI2
AccessionNM_145043
Cytogenetic8p23.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNEIL2 Full-Length MS Protein Standard (NP_659480), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 )

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