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ARHGDIA Full-Length MS Protein Standard

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Product Description


NameARHGDIA Full-Length MS Protein Standard
Cat#CPFL300902
Protein NameRho GDP dissociation inhibitor (GDI) alpha
SymbolARHGDIA
SynonymsGDIA1; HEL-S-47e; NPHS8; RHOGDI; RHOGDI-1
AccessionNM_004309
Cytogenetic17q25.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionARHGDIA Full-Length MS Protein Standard (NP_004300), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

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