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LAMTOR2 Full-Length MS Protein Standard

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Product Description


NameLAMTOR2 Full-Length MS Protein Standard
Cat#CPFL300862
Protein Namelate endosomal/lysosomal adaptor, MAPK and MTOR activator 2
SymbolLAMTOR2
SynonymsENDAP; HSPC003; MAPBPIP; MAPKSP1AP; p14; Ragulator2; ROBLD3
AccessionNM_014017
Cytogenetic1q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionROBLD3 Full-Length MS Protein Standard (NP_054736), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

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